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Proteomic Identification of Protein Misexpression During Cardiogenesis in the Ts65Dn Down Syndrome Mouse Model
Down syndrome (DS), a complex genetic disorder in humans, is due to the triplication of human chromosome 21 and results in congenital heart defects in approximately 50% of DS newborns. The Ts65Dn mouse model has various ...
Evaluation of endochondral skeletogenesis in the Ts65Dn mouse model for Down syndrome during embryonic development
Down syndrome (DS) is a complex genetic disorder caused by the triplication of human chromosome 21. This disorder has been linked to numerous abnormalities affecting nearly every system in the body. Phenotypes pertaining ...